Star striker Sadio Mane survived a second-half clash of heads with Cape Verde goalkeeper Vorzinha to put his side ahead in their round of 16 game at the Baffoussam Stadium.
The Liverpool forward suffered what looked like concussion after the clash that saw the goalkeeper sent off.
Both players challenged for an aerial ball and ended up on the turf, with Mane looking dazed as he crumpled to ground.
Vorzinha was the worse for wear as he was taken out and then shown a red card after VAR showed he was at fault.
Despite him looking uncomfortable, Senegal opted to leave Mane on the pitch, and he scored the opener six minutes later.
He was substituted shortly after he fell on the field once again, raising concerns over a potential case of concussion.
Cape Verde had already been reduced to ten men in the first half when Patrick Andrade was sent off for a dangerous tackle, leaving his side to defend for most of the game.
After Mane scored the opener, the Senegalese doubled their lead in time added on and the end of the second half through Bamba Dieng.
Tuesday’s matches also paid homage to the fans who died after a stampede during Monday’s game between Cameroon and Comoros at the Olembe Stadium.
